Current Issues in Depression in Parkinson's Disease
Identifieur interne : 001D01 ( Main/Exploration ); précédent : 001D00; suivant : 001D02Current Issues in Depression in Parkinson's Disease
Auteurs : Theresa A. Zesiewicz [États-Unis] ; Michael Gold [États-Unis] ; Ganesh Chari [États-Unis] ; Robert A. Hauser [États-Unis]Source :
- The American Journal of Geriatric Psychiatry [ 1064-7481 ] ; 1998.
Abstract
Depression affects 4050 of Parkinson's disease (PD) patients. The authors, by use of a Mednet and manual search of pertinent literature, summarize current issues in the treatment of depression in PD. Open-label studies suggest that antidepressants may be effective for treating depression in PD. Although case reports indicate that selective serotonin reuptake inhibitors (SSRIs) can potentially worsen the motor symptoms of PD, this effect has not been confirmed in the small number of open-label studies that have been performed to date. The occurrence of the serotonin syndrome resulting from a combination of selegiline and an SSRI appears to be rare. Double-blind prospective studies are needed to evaluate the safety and efficacy of antidepressants in PD and their effect on motor function.
Url:
DOI: 10.1097/00019442-199905000-00003
Affiliations:
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Zesiewicz</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Floride</region></placeName><wicri:cityArea>Parkinson's Disease and Movement Disorders Center, Tampa</wicri:cityArea></affiliation></author><author><name sortKey="Gold, Michael" sort="Gold, Michael" uniqKey="Gold M" first="Michael" last="Gold">Michael Gold</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Floride</region></placeName><wicri:cityArea>Parkinson's Disease and Movement Disorders Center, Tampa</wicri:cityArea></affiliation></author><author><name sortKey="Chari, Ganesh" sort="Chari, Ganesh" uniqKey="Chari G" first="Ganesh" last="Chari">Ganesh Chari</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Floride</region></placeName><wicri:cityArea>Parkinson's Disease and Movement Disorders Center, Tampa</wicri:cityArea></affiliation></author><author><name sortKey="Hauser, Robert A" sort="Hauser, Robert A" uniqKey="Hauser R" first="Robert A." last="Hauser">Robert A. Hauser</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Floride</region></placeName><wicri:cityArea>Parkinson's Disease and Movement Disorders Center, Tampa</wicri:cityArea></affiliation></author></analytic><monogr></monogr><series><title level="j">The American Journal of Geriatric Psychiatry</title><title level="j" type="abbrev">AMGP</title><idno type="ISSN">1064-7481</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1998">1998</date><biblScope unit="volume">7</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="110">110</biblScope><biblScope unit="page" to="118">118</biblScope></imprint><idno type="ISSN">1064-7481</idno></series><idno type="istex">437EFFEF2C350B16AA41EF7FA65ED538ECBE895F</idno><idno type="DOI">10.1097/00019442-199905000-00003</idno><idno type="PII">S1064-7481(12)61204-4</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1064-7481</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">Depression affects 4050 of Parkinson's disease (PD) patients. The authors, by use of a Mednet and manual search of pertinent literature, summarize current issues in the treatment of depression in PD. Open-label studies suggest that antidepressants may be effective for treating depression in PD. Although case reports indicate that selective serotonin reuptake inhibitors (SSRIs) can potentially worsen the motor symptoms of PD, this effect has not been confirmed in the small number of open-label studies that have been performed to date. The occurrence of the serotonin syndrome resulting from a combination of selegiline and an SSRI appears to be rare. Double-blind prospective studies are needed to evaluate the safety and efficacy of antidepressants in PD and their effect on motor function.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Floride</li></region></list><tree><country name="États-Unis"><region name="Floride"><name sortKey="Zesiewicz, Theresa A" sort="Zesiewicz, Theresa A" uniqKey="Zesiewicz T" first="Theresa A." last="Zesiewicz">Theresa A. Zesiewicz</name></region><name sortKey="Chari, Ganesh" sort="Chari, Ganesh" uniqKey="Chari G" first="Ganesh" last="Chari">Ganesh Chari</name><name sortKey="Gold, Michael" sort="Gold, Michael" uniqKey="Gold M" first="Michael" last="Gold">Michael Gold</name><name sortKey="Hauser, Robert A" sort="Hauser, Robert A" uniqKey="Hauser R" first="Robert A." last="Hauser">Robert A. Hauser</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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